Specific small RNA pathways protect germ line from transposons

Cells of higher organisms are in a constant struggle against some of their own DNA - repeated bits of DNA sequence called transposons that have infiltrated host genomes over the eons. Transposons damage the rest of the genome ...

Study yields rich dossier of cancer-linked protein's associates

Proteins often don't do anything in our cells by themselves. Their role in a given physiological process - good or bad - is typically determined by binding to one or more other proteins. So as researchers try to figure out ...

Using rooster testes to learn how the body fights viruses

Our bodies are constantly under siege by foreign invaders; viruses, bacteria and parasites that want to infiltrate our cells. A new study in the journal eLife sheds light on how germ cells - sperm and egg - protect themselves ...

Understanding how cells defend their genome against invaders

Researchers at the University of Tokyo have uncovered more details about the tiny defenders that ensure fertility by protecting the genomes of specialized cells called germ cells, which produce eggs and sperm. The complex ...

Egg Cetera #1: The immortal egg

In the first report of our Egg Cetera series on egg-related research, biologists Dr. Harry Leitch and Professor Azim Surani describe how advances in understanding egg development could transform reproductive and regenerative ...

Learning how cells respond to stressful conditions

Developing approaches to protect human well-being in a changing climate will depend on a deeper understanding of how mammalian cells and organisms adapt to dramatic shifts in temperature and in the availability of food and ...

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