CRISPR-based genetic screens have helped scientists identify genes that are key players in sickle-cell anemia, cancer immunotherapy, lung cancer metastasis, and many other diseases. However, these genetic screens are limited ...
Biotechnology
Mar 16, 2020
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2615
Defects in tRNA biogenesis influence gene expression and are associated with many types of human diseases, such as cancer and neurological diseases. In his thesis, Fu Xu contributes to new knowledge about the factors that ...
Molecular & Computational biology
Jan 16, 2020
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4
Scientists routinely use genetic screens to perturb, or change the activity of, genes in mammalian cells, one at a time, to learn what those genes do. Pooled screens take this same approach but typically involve many more ...
Molecular & Computational biology
Oct 18, 2019
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34
Using a new approach to genetic screening with CRISPR, researchers at the Crick have identified key genes for the survival of the parasite Toxoplasma gondii in mice.
Biotechnology
Sep 3, 2019
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156
Like finding a needle in a haystack, identifying genes that are involved in particular diseases can be an arduous and time consuming process. Looking to improve this process, a team led by researchers at Baylor College of ...
Biotechnology
Apr 30, 2019
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9
Scientists at McMaster University have discovered several new biomarkers from a single drop of blood that could allow earlier and more definitive detection of cystic fibrosis (CF), a genetic disease which strikes both children ...
Biochemistry
Dec 20, 2018
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12
Dying cells generally have two options: go quietly, or go out with a bang.
Cell & Microbiology
Jun 7, 2018
0
356
Scientist at IMBA developed a biobank of revertible, mutant embryonic stem cells, published in the current issue of Nature. This cell bank – called Haplobank - contains over 100,000 mutated, conditional mouse embryonic ...
Cell & Microbiology
Sep 28, 2017
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158
The use of molecular-assisted alpha taxonomy (MAAT) has helped to distinguish species of the Bossiella genus of red algae. Whereas a morphological study showed four Bossiella species in the eastern Pacific Ocean, this genetic ...
Plants & Animals
Nov 20, 2014
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0
A specially formed material that can provide custom broadband absorption in the infrared can be identified and manufactured using "genetic algorithms," according to Penn State engineers, who say these metamaterials can shield ...
Nanophysics
May 5, 2014
0
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