A CRISPR pioneer looks back as the first gene-editing therapy is approved
In 2007, Luciano Marraffini struck out on what was then a scientifically lonely path: to understand CRISPR, which had been discovered in bacteria only about a decade before.
In 2007, Luciano Marraffini struck out on what was then a scientifically lonely path: to understand CRISPR, which had been discovered in bacteria only about a decade before.
Cell & Microbiology
Dec 14, 2023
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12
Researchers have sequenced the whitebark pine genome, presenting new opportunities to help the threatened, high-altitude tree endure environmental challenges.
Ecology
Dec 14, 2023
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A multidisciplinary study published in Nature has elucidated the structure of the machinery responsible for writing much of our "dark genome"—the 98% of our DNA that has largely unknown biological function. These results ...
Biotechnology
Dec 14, 2023
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160
University of Pittsburgh researchers have developed a new embryo-like model derived from adult cells that replicates key features of early human development, including the generation of blood cells.
Cell & Microbiology
Dec 13, 2023
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A team of engineers at Duke University have developed a method to broaden the reach of CRISPR technologies. While the original CRISPR system could only target 12.5% of the human genome, the new method expands access to nearly ...
Biotechnology
Dec 5, 2023
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428
Far too many antibiotics are used around the world. As a result, bacteria are becoming resistant to these drugs. Curing bacterial diseases is becoming more difficult than before because antibiotics are perhaps our foremost ...
Cell & Microbiology
Nov 28, 2023
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26
RNA (ribonucleic acid), which is made up of ribonucleotides, is a molecule found in all living organisms. RNA is thought to have probably preceded DNA in primordial life billions of years ago. RNA was eventually replaced ...
Molecular & Computational biology
Nov 27, 2023
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1
The research team of Professor Petra Beli and their collaborators have discovered that aldehydes, a type of toxic chemical produced by the body after drinking alcohol, damage cells by creating chemical crosslinks between ...
Cell & Microbiology
Nov 22, 2023
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103
The Pomoideae subfamily includes nutritionally valuable pome fruits like apples and pears, and their genetic diversity is critical for the enhancement of fruit crops. Current research has made strides in intergeneric hybridization ...
Molecular & Computational biology
Nov 21, 2023
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In a recent article published in Molecular Cell, Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, and Yuki Aoi Ph.D., a postdoctoral fellow in Shilatifard laboratory, ...
Cell & Microbiology
Nov 3, 2023
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