Protein abundant in cancerous cells causes DNA 'supercoiling'
A team of USC scientists has identified a protein that can change DNA topology, making DNA twist up into a so-called "supercoil."
Cell & Microbiology
Mar 11, 2013
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Page 7 - News tagged with gene structure
Selectively manipulating protein modifications
Protein activity is strictly regulated. Incorrect or poor protein regulation can lead to uncontrolled growth and thus cancer or chronic inflammation. Members of the Institute of Veterinary Biochemistry and Molecular Biology ...
Cell & Microbiology
Mar 10, 2013
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DNA's twisted communication: Genome organization key element for control of gene expression
During embryo development, genes are dynamically, and very precisely, switched on and off to confer different properties to different cells and build a well-proportioned and healthy animal. Fgf8 is one of the key genes in ...
Biotechnology
Feb 28, 2013
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New type of gene that regulates tumor suppressor PTEN identified
Small stretches of DNA in the human genome are known as "pseudogenes" because, while their sequences are nearly identical to those of various genes, they have long been thought to be non-coding "junk" DNA.
Cell & Microbiology
Feb 24, 2013
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It takes two to tangle: Scientists further unravel telomere biology
Chromosomes - long, linear DNA molecules – are capped at their ends with special DNA structures called telomeres and an assortment of proteins, which together act as a protective sheath. Telomeres are maintained through ...
Cell & Microbiology
Nov 21, 2012
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Metals in the genetic forge: Detailed views of RNA splicing
Scientists at Yale University have described in the greatest detail yet aspects of the chemical processes by which RNA carries out the expression of our genes.
Cell & Microbiology
Oct 29, 2012
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Unusual genetic structure confers major disease resistance trait in soybean
Scientists have identified three neighboring genes that make soybeans resistant to the most damaging disease of soybean. The genes exist side-by-side on a stretch of chromosome, but only give resistance when that stretch ...
Biotechnology
Oct 11, 2012
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Discovery of essential genes for drug-resistant bacteria reveals new, high-value drug targets
(Phys.org)—Biomedical scientists collaborating on translational research at two Buffalo institutions are reporting the discovery of a novel, and heretofore unrecognized, set of genes essential for the growth of potentially ...
Biotechnology
Sep 14, 2012
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Gene's function may give new target for cancer drugs
(Phys.org)—Purdue University scientists have determined that a gene long known to be involved in cancer cell formation and chemotherapy resistance is key to proper RNA creation, an understanding that could one day lead ...
Biochemistry
Sep 12, 2012
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Weapon-wielding marine microbes may protect populations from foes
Competition is a strong driving force of evolution for organisms of all sizes: Those individuals best equipped to obtain resources adapt and reproduce, while others may fall by the wayside. Many organisms—mammals, birds ...
Cell & Microbiology
Sep 6, 2012
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