In eukaryotic cells, the genomic DNA is hierarchically packaged by histones into chromatin. Chromatin structure and its plasticity play an important role in the activation and silencing of gene transcription, and determine ...
Cell & Microbiology
Jul 29, 2020
0
18
Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA. Since the discovery of the ...
Cell & Microbiology
Apr 7, 2023
0
56
Scientists at UMass Medical School, the Institut Curie in Paris and Stanford University, have taken a detailed look inside the small, densely packed structure of the inactive X chromosome found in female mammals called the ...
Biotechnology
Jul 21, 2016
0
109
CRISPR has been hailed as one of the most promising gene editing technologies and promises to revolutionize precision medicine and eradicate genetic diseases. However, the technique is not perfect and needs improvements. ...
Biotechnology
Apr 9, 2018
0
32
When Profs. Joel Sussman and Israel Silman were asked to mentor Chinese students online during the COVID-19 pandemic, the last thing they expected to come out of the experience was highly innovative research on protein evolution ...
Biotechnology
Feb 14, 2024
0
25
A team of researchers at the IRCM led by François Robert, PhD, uncovered a critical role for two proteins in chromatin structure. Their breakthrough, recently published in the scientific journal Molecular Cell, helps explain ...
Cell & Microbiology
May 26, 2015
0
66
New insights into a little-understood DNA structure could provide the basis for new cancer therapies.
Biotechnology
Mar 18, 2021
0
54
What is and is not possible for natural evolution may be explained using models and calculations from theoretical physics, say researchers in Japan.
General Physics
May 29, 2020
0
16
A genome by itself is like a recipe without a chef—full of important information, but in need of interpretation. So, even though we have sequenced genomes of our nearest extinct relatives—the Neanderthals and the Denisovans—there ...
Molecular & Computational biology
Apr 26, 2021
0
104
A yeast protein that evolved from scratch can fold into a three-dimensional shape—contrary to the general understanding of young proteins—according to new research led by the University of Arizona.
Biochemistry
Oct 20, 2017
1
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