While the number of coding genes that produce proteins in humans has dwindled to 20,000 in recent years, scientists think that the dimensions of the proteome could be larger. This diversity of proteins has become one of the ...
Biochemistry
Oct 4, 2016
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A terrific article recently published in Molecular Biology and Evolution, "Alternative Splice in Alternative Lice," provides a compelling example of maximizing genome information – adaptation of the louse Pediculus humanus ...
Ecology
Aug 7, 2015
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7
Researchers at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna as well as at the University of Natural Resources and Life Sciences (BOKU) in Vienna have discovered an entirely ...
Biotechnology
Jun 11, 2015
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Certain diseases such as cystic fibrosis and muscular dystrophy are linked to genetic mutations that damage the important biological process of rearranging gene sequences in pre-messenger RNA, a procedure called RNA splicing.
Cell & Microbiology
Sep 26, 2013
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2
"You look at the material world and see objects and how you can use them. I look at the material world and see a fascinating hidden life which is within our control, if we can only understand how it works," says Jane Lipson, ...
Polymers
Nov 16, 2012
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Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing - a critical step in the earliest stage of protein production. Their study appears in the ...
Cell & Microbiology
Sep 23, 2010
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Researchers in human genetics have long known that expansions of GAA repeats - resulting in this nucleotide triplet repeating hundreds or thousands of times - cause the most common hereditary neurological disorder known as ...
Cell & Microbiology
Jul 9, 2009
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With the development of genome sequencing technologies, many long non-coding RNAs (lncRNAs) have been identified in fruits and vegetables. Extensive research on lncRNAs has revealed their roles in regulating the expression ...
Molecular & Computational biology
May 9, 2024
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Researchers at Montana State University have found a method for creating more robust, temperature-tolerant enzymes that can be used as tools in the process of genetic manipulation.
Biotechnology
Sep 7, 2012
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The widely-used Affymetrix Whole-Transcript Gene 1.0 ST (sense target) microarray platform, normally used to assay gene expression, can also be utilized to interrogate exon-specific splicing. Research published today in the ...
Other
May 21, 2009
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