New insights into cooperativity in gene regulation

In a study published in Nature, Dirk Schübeler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) describe how the interplay between transcription factors and epigenetic modifications of DNA ...

Novel histone modifications couple metabolism to gene activity

Scientists of Helmholtz Zentrum München and Ludwig-Maximilians-Universität Munich (LMU) have discovered that two new classes of histone modifications couple cellular metabolism to gene activity. The study was published ...

Selectively manipulating protein modifications

Protein activity is strictly regulated. Incorrect or poor protein regulation can lead to uncontrolled growth and thus cancer or chronic inflammation. Members of the Institute of Veterinary Biochemistry and Molecular Biology ...

Lessons learned from yeast about human leukemia

The trifecta of biological proof is to take a discovery made in a simple model organism like baker's yeast and track down its analogs or homologs in "higher" creatures right up the complexity scale to people, in this case, ...

Can gene editing provide a solution to global hunger?

According to the World Food Program, some 795 million people – one in nine people on earth – don't have enough food to lead a healthy active life. That will only get worse with the next global food crisis, predicted to ...

Regulating genome-edited crops that aren't GMOs

A survey of rice, wheat, barley, fruit, and vegetable crops found that most mutants created by advanced genetic engineering techniques may be out of the scope of current genetically modified organism (GMO) regulations. In ...

Tomato gene may fend banana against formidable fungus

(PhysOrg.com) -- Proteins from the fungus Cladosporium fulvum, which causes leaf blight in tomato plants, are very similar to the proteins of the fungus Mycosphaerella fijiensis, which causes the much-feared black Sigatoka ...

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