Despite enormous efforts to advance traditional pharmacology approaches, more than three quarters of all human proteins remain beyond the reach of therapeutic development. Targeted protein degradation (TPD) is a novel approach ...
Biochemistry
Aug 3, 2020
0
45
Scientists in Canada, the United States and Europe are looking to rewrite the textbook on microbial ecology, advocating a new approach to studying the most abundant form of life on Earth.
Ecology
Apr 16, 2018
0
110
(PhysOrg.com) -- UNSW students have sequenced the chloroplast genome of the ancient Wollemi Pine - a world first that could reveal how a "dinosaur" of the tree kingdom survived 200 million years of shifting continents and ...
Biotechnology
Dec 17, 2009
0
0
For decades, scientists and doctors have known that bacteria in soil were capable of manufacturing streptozotocin, an antibiotic compound that is also an important treatment for certain types of pancreatic cancer.
Biochemistry
Feb 7, 2019
0
148
Differences in the geographic origin of genes may affect the function of human mitochondria—energy-generating organelles inside of cells—according to a new study. Mitochondria have their own genome, separate from the ...
Ecology
Jan 14, 2019
0
83
(Phys.org) —University of Florida researchers have developed a "DNA nanotrain" that fast-tracks its payload of cancer-fighting drugs and bioimaging agents to tumor cells deep within the body. The nanotrain's ability to ...
Bio & Medicine
Apr 30, 2013
0
0
Much of the research in the field of plant functional genomics to date has relied on approaches based on single reference genomes. But by itself, a single reference genome does not capture the full genetic variability of ...
Biotechnology
Dec 20, 2017
0
74
How do fetal cells know what cell types to become? Why do cells in the adult body sometimes forget what they are and develop into cancer cells? These are some of the questions intensively investigated within the research ...
Cell & Microbiology
Nov 7, 2011
0
0
It was like a map of New York missing all of Manhattan. The human reference genome finally has all its blank spots filled in, and seeing everything we missed the first time around is both repetitive—and enlightening.
Molecular & Computational biology
Mar 31, 2022
1
293
In a new study published in Nature Communications, Associate Professor Tuo Wang and his research team from the Department of Chemistry at Louisiana State University revealed the molecular architecture of fungal cell walls ...
Molecular & Computational biology
Nov 15, 2021
0
92
