Chemists discover structure of glucagon fibrils

Patients with type 1 diabetes have to regularly inject themselves with insulin, a hormone that helps their cells absorb glucose from the bloodstream. Another hormone called glucagon, which has the opposite effect, is given ...

Collagen fibres grow like a sunflower

Collagen fibrils are a major component of the connective tissues found throughout the animal kingdom. The cable-like assemblies of long biological molecules combine to form tissues as varied as skin, corneas, tendons or bones. ...

Technique uses well-known dye to watch amyloid plaques in the brain

While amyloid plaques have long been closely associated with mechanisms driving Alzheimer's disease, visualizing how amyloid proteins assemble continues to prove difficult. The nanometer-sized amyloid fibrils are only a fraction ...

A boundary dance of amyloid-β stepping into dementia

Alzheimer's disease is caused by aggregates of amyloid-β (Aβ) peptides. This aggregation is accelerated at the cell membrane surface. Using molecular dynamics simulations and NMR experiments, the research group at ExCELLS ...

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