Some 50 years have passed since scientists first proposed the so-called 'inside–outside model' of development, which holds that the inner cells of the early embryo eventually form all the definitive structures of the fetus, ...
Cell & Microbiology
Apr 10, 2013
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The field of regenerative medicine holds great promise, propelled by greater understanding of how stem cells differentiate themselves into many of the body's different cell types. But clinical applications in the field have ...
Materials Science
Mar 28, 2013
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Researchers at the A*STAR Institute of Medical Biology (IMB) have discovered a critical checkpoint protein that controls when human embryonic stem cells (hESCs) begin to differentiate.
Cell & Microbiology
Feb 27, 2013
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Every gene in the nucleus of an animal or plant cell is packaged into a beads-on-a-string like structure called nucleosomes: the DNA of the gene forms the string and a complex of proteins called histones forms the beads around ...
Biotechnology
Feb 11, 2013
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Chromatin remodeling—the packaging and unpackaging of genomic DNA and its associated proteins—regulates a host of fundamental cellular processes including gene transcription, DNA repair, programmed cell death as well ...
Biochemistry
Nov 29, 2012
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Notch – the protein that can help determine cell fate – maintains a stable population of basal cells in the prostate through a positive feedback loop system with another key protein – TGF beta (transforming growth factor ...
Cell & Microbiology
Nov 1, 2012
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A new study combining the latest archaeological evidence with state-of-the-art geoscience technologies provides evidence that climate change was a key ingredient in the collapse of the great Indus or Harappan Civilization ...
Earth Sciences
May 28, 2012
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What happens to a stem cell at the molecular level that causes it to become one type of cell rather than another? At what point is it committed to that cell fate, and how does it become committed? The answers to these questions ...
Cell & Microbiology
Apr 12, 2012
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The fate of the world's great whale species commands global attention as a result of heated debate between pro and anti-whaling advocates, but the fate of smaller marine mammals is less understood, specifically because the ...
Ecology
Jan 24, 2012
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(PhysOrg.com) -- An international team of biochemists, biophysicists, and neutron scientists are using a combination of fluorescence and small-angle neutron scattering (SANS) techniques to assist biochemists in better understanding ...
Biochemistry
Dec 15, 2011
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