Cells find their identity using a mathematically optimal strategy

Organisms are made of many types of cells arranged in a precise and reproducible spatial pattern that gives rise to properly formed and well-functioning tissues and organs. But how do genetically identical cells in an organism ...

Novel probe for metabolic diseases

NUS pharmaceutical scientists have developed a simple, yet highly sensitive probe to detect the fat mass and obesity-associated protein (FTO) levels in cells. This can potentially help in the early detection and diagnosis ...

New CRISPR tool targets RNA in mammalian cells

Researchers from the Broad Institute of MIT and Harvard have shown that a CRISPR-based editing system can cut and bind RNA in mammalian cells. In a paper out this week in Nature, the team used CRISPR-Cas13, which the researchers ...

Lizard blizzard survivors tell story of natural selection

An unusually cold winter in the U.S. in 2014 took a toll on the green anole lizard, a tree-dwelling creature common to the southeastern United States. A new study offers a rare view of natural selection in this species, showing ...

Tweaking the transcriptome to tackle stress

Single-celled plankton known as dinoflagellates are shown to cope with stress using an unexpected strategy of editing their RNA rather than changing gene expression levels.

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