Discovery of a cellular uptake pathway for larger drug molecules

Recent findings by UCSF and Arc Institute scientists open up new possibilities for overcoming a fundamental challenge in drug discovery. There can be a tradeoff between optimizing a drug's key-in-a-lock fit with its target ...

Artificial gravity provides partial protection for biology in space

Space travel to the moon, Mars, and beyond can expose astronauts to extreme conditions, causing potential health issues. To prepare for future long-duration missions, NASA studies how the effects of space—changes in gravity, ...

Adjusting the balance of X-chromosome dosage

A new study by researchers at Karolinska Institutet identify major sex differences in the timing of X chromosome upregulation, a finding that is vital for understanding central gene-regulatory processes in early fetal development. ...

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