The effectiveness of any drug molecule depends on how well it interacts with the internal environment inside our body. Its pharmacokinetic (PK) properties determine how successfully it escapes degrading enzymes as it travels ...
Biochemistry
Oct 10, 2023
0
54
Enzymes, the micro machines in our cells, can evolve to perform new tasks when confronted with novel situations. But what if you want an enzyme to do an entirely different job—one that it would never have to do in a cell? ...
Biochemistry
Apr 22, 2015
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32
Everything a cell does, from dividing in two to migrating to a different part of the body, is controlled by enzymes that chemically modify other proteins in the cell. Researchers at Princeton University have devised a new ...
Molecular & Computational biology
Feb 13, 2020
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205
Highlighting an important but unexplored area of evolution, scientists at The Scripps Research Institute (TSRI) have found evidence that, over hundreds of millions of years, an essential protein has evolved chiefly by changing ...
Cell & Microbiology
Sep 29, 2013
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0
Recent studies conducted at Marshall University have demonstrated that nanoparticles of cerium oxide -- common diesel fuel additives used to increase the fuel efficiency of automobile engines -- can travel from the lungs ...
Bio & Medicine
Nov 17, 2011
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0
Scientists have sequenced the genomes of nearly 6,900 organisms, but they know the functions of only about half of the protein-coding genes thus far discovered. Now a multidisciplinary effort involving 15 scientists from ...
Cell & Microbiology
Sep 23, 2013
1
0
(PhysOrg.com) -- A new study of the CRYM protein, previously connected with deafness and cancer, has now proven that it has an enzymatic function. This opens up new implications for the treatment of neurological and psychiatric ...
Biochemistry
Jan 11, 2012
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1
(PhysOrg.com) -- UC Irvine researchers have discovered that circadian rhythms - our own body clock - regulate energy levels in cells. The findings have far-reaching implications, from providing greater insights into the bond ...
Cell & Microbiology
Mar 12, 2009
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0
Chemists from Nijmegen, The Netherlands, have developed a catalyst that binds to DNA, slides over it and splits the molecule in particular places. The researchers were able to do this by synthetically modifying a natural ...
Materials Science
Sep 24, 2013
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0
Just as a breeze causes leaves, branches and ultimately the tree to move, enzymes moving at the molecular level perform hundreds of chemical processes that have a ripple effect necessary for life. Protein complexes are often ...
Cell & Microbiology
Nov 8, 2011
6
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