Twenty-year protein mystery solved with surprising results

(PhysOrg.com) -- A new study of the CRYM protein, previously connected with deafness and cancer, has now proven that it has an enzymatic function. This opens up new implications for the treatment of neurological and psychiatric ...

Mathematical model reveals behavior of cellular enzymes

Everything a cell does, from dividing in two to migrating to a different part of the body, is controlled by enzymes that chemically modify other proteins in the cell. Researchers at Princeton University have devised a new ...

Chemists slide a splitting catalyst over DNA for the first time

Chemists from Nijmegen, The Netherlands, have developed a catalyst that binds to DNA, slides over it and splits the molecule in particular places. The researchers were able to do this by synthetically modifying a natural ...

Engineering the P450 enzyme to perform new reactions

Enzymes, the micro machines in our cells, can evolve to perform new tasks when confronted with novel situations. But what if you want an enzyme to do an entirely different job—one that it would never have to do in a cell? ...

Body clock regulates metabolism

(PhysOrg.com) -- UC Irvine researchers have discovered that circadian rhythms - our own body clock - regulate energy levels in cells. The findings have far-reaching implications, from providing greater insights into the bond ...

Fundamental discovery casts enzymes in new light

Just as a breeze causes leaves, branches and ultimately the tree to move, enzymes moving at the molecular level perform hundreds of chemical processes that have a ripple effect necessary for life. Protein complexes are often ...

Proteins prove their metal

(PhysOrg.com) -- The word 'metal' conjures up images of machines and heavy industry but metals are also intimately involved in the biological processes that regulate our bodies and underpin new energy technologies.

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