Scientists have broken the rules of enzyme engineering to unlock a new method for creating chemical reactions that could unlock a wide range of new applications—from creating new drugs to food production.
Biochemistry
Dec 1, 2020
0
2132
In overgrown areas from Canada to China, a lush, woody vine with crescent-shaped seeds holds the secret to making a cancer-fighting chemical. Now, Whitehead Institute researchers in Member Jing-Ke Weng's lab have discovered ...
Biotechnology
Apr 20, 2020
0
44
Everything a cell does, from dividing in two to migrating to a different part of the body, is controlled by enzymes that chemically modify other proteins in the cell. Researchers at Princeton University have devised a new ...
Molecular & Computational biology
Feb 13, 2020
0
205
A deep learning-powered computational framework, 'DeepEC,' will allow the high-quality and high-throughput prediction of enzyme commission numbers, which is essential for the accurate understanding of enzyme functions.
Machine learning & AI
Jul 9, 2019
0
0
For decades, scientists and doctors have known that bacteria in soil were capable of manufacturing streptozotocin, an antibiotic compound that is also an important treatment for certain types of pancreatic cancer.
Biochemistry
Feb 7, 2019
0
148
A research team from Ruhr-Universität Bochum (RUB) and from South Africa has analysed two enzymes with identical substrate binding pockets that nevertheless convert different substrates. In the process, it emerged that changes ...
Biochemistry
Nov 7, 2018
0
6
Nicotinamide adenine dinucleotide (NAD+) is a major player in nutrition today. Studies have shown that NAD+ concentrations decrease during aging and that recovering the body's levels of NAD+ can prolong both health span and ...
Biochemistry
Oct 24, 2018
0
73
Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide.
Biochemistry
Jan 18, 2018
0
9
In a large multidisciplinary project, researchers at Karolinska Institutet have explored different properties of an enzyme family called NUDIX hydrolases. The study, published in Nature Communications, reveals novel insights ...
Biochemistry
Nov 17, 2017
0
2
The catalytic activity of an enzyme called Set1A—a protein that is essential to the viability of embryonic stem cells (ESCs)—is not required for ESC self-renewal, according to a Northwestern Medicine study published in ...
Biotechnology
Oct 2, 2017
0
3
