Organoids produce embryonic heart

There was a time when the idea of growing organs in the lab was the stuff of science fiction. Today, stem cell biology and tissue engineering are turning fiction into reality with the advent of organoids: tiny lab-grown tissues ...

Embryos taking shape via buckling

The embryo of an animal first looks like a hollow sphere. Invaginations then appear at different stages of development, which will give rise to the body's structures (the brain, digestive tract, etc.). According to a hypothesis ...

Epigenetics and cell diversity in the embryo

A research team at the Max Planck Institute for Molecular Genetics in Berlin has explored the role of factors in embryonic development that do not alter the sequence of DNA, but only epigenetically modify its "packaging". ...

Unprecedented single-cell studies in virtual embryo

"How are the many different cell types in the body generated during embryonic development from an egg, which is only a single cell? This is one of the most fundamental questions in biology," explains Dr. Pierre Neveu, group ...

How some mammals pause their pregnancies

How do some mammals postpone the development of their embryos to await better conditions for having offspring? A recent study at the UW Medicine Institute for Stem Cell and Regenerative Medicine explored this reproductive ...

Tracking life's first step: Two molecules 'awaken' brand new genome

Within hours after fertilization, a unique genome forms from chromosomes contributed by the egg and sperm. However, this new genome is initially inactive and must be "awakened" to begin the transcription of its DNA and start ...

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