Zebrafish swim into drug development

By combining the tools of medicinal chemistry and zebrafish biology, a team of Vanderbilt investigators has identified compounds that may offer therapeutic leads for bone-related diseases and cancer.

Environmental oxygen triggers loss of webbed digits

Free fingers have many obvious advantages on land, such as in locomotion and grasping, while webbed fingers are typical of aquatic or gliding animals. But both amphibians and amniotes—which include mammals, reptiles, and ...

Study finds why many IVF embryos fail to develop

In humans, a fertilized egg is no guarantee of reproductive success. Most embryos stop developing and perish within days of fertilization, usually because they have an abnormal number of chromosomes. Now, researchers at Columbia ...

Unprecedented single-cell studies in virtual embryo

"How are the many different cell types in the body generated during embryonic development from an egg, which is only a single cell? This is one of the most fundamental questions in biology," explains Dr. Pierre Neveu, group ...

New sensor to aid in vitro fertilization

The tricky process of monitoring early-stage embryos during the in vitro fertilization process could become much easier with the development of a new fibre-optic sensor that can measure concurrently, hydrogen peroxide and ...

Mother controls embryo's gene activity

Frog embryos do not fully control which genes they can turn on or off in the beginning of their development – but their mother does, through specific proteins in the egg cell. Molecular developmental biologists at Radboud ...

Researchers piggyback to safer reprogrammed stem cells

Austin Smith and his research team at the Centre for Stem Cell Research in Cambridge have just published in the journal Development a new and safer way of generating pluripotent stem cells - the stem cells that can give rise ...

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