Zebrafish swim into drug development
By combining the tools of medicinal chemistry and zebrafish biology, a team of Vanderbilt investigators has identified compounds that may offer therapeutic leads for bone-related diseases and cancer.
By combining the tools of medicinal chemistry and zebrafish biology, a team of Vanderbilt investigators has identified compounds that may offer therapeutic leads for bone-related diseases and cancer.
Biochemistry
Jan 21, 2010
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Free fingers have many obvious advantages on land, such as in locomotion and grasping, while webbed fingers are typical of aquatic or gliding animals. But both amphibians and amniotes—which include mammals, reptiles, and ...
Ecology
Jun 13, 2019
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102
In humans, a fertilized egg is no guarantee of reproductive success. Most embryos stop developing and perish within days of fertilization, usually because they have an abnormal number of chromosomes. Now, researchers at Columbia ...
Cell & Microbiology
Jul 19, 2022
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Studied for decades for their essential role in making proteins within cells, several amino acids known as tRNA synthetases were recently found to have an unexpected – and critical – additional role in cancer metastasis ...
Biochemistry
Mar 4, 2013
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"How are the many different cell types in the body generated during embryonic development from an egg, which is only a single cell? This is one of the most fundamental questions in biology," explains Dr. Pierre Neveu, group ...
Cell & Microbiology
Apr 20, 2020
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107
Scientists have identified key molecular events in the developing human embryo between days 7 and 14—one of the most mysterious, yet critical, stages of our development.
Biotechnology
Jun 17, 2021
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143
The tricky process of monitoring early-stage embryos during the in vitro fertilization process could become much easier with the development of a new fibre-optic sensor that can measure concurrently, hydrogen peroxide and ...
Engineering
Jan 5, 2016
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A novel approach in the study of the development of mammalian embryos was today reported in the journal Nature Communications. The research, from the laboratory of Professor Magdalena Zernicka-Goetz of the University of Cambridge, ...
Cell & Microbiology
Feb 14, 2012
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Frog embryos do not fully control which genes they can turn on or off in the beginning of their development – but their mother does, through specific proteins in the egg cell. Molecular developmental biologists at Radboud ...
Cell & Microbiology
Dec 18, 2015
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Austin Smith and his research team at the Centre for Stem Cell Research in Cambridge have just published in the journal Development a new and safer way of generating pluripotent stem cells - the stem cells that can give rise ...
Cell & Microbiology
Feb 27, 2009
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