Quality control of mitochondria as a defense against disease

Scientists from the Montreal Neurological Institute and Hospital in Canada have discovered that two genes linked to hereditary Parkinson's disease are involved in the early-stage quality control of mitochondria. The protective ...

Study reveals how to better master stem cells' fate

(Phys.org) —USC scientist Qi-Long Ying and a team of researchers have long been searching for biotech's version of the fountain of youth—ways to encourage embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs) to ...

A protein that can mean life or death for cells

Each cell in an organism has a sensor that measures the health of its "internal" environment. This "alarm" is found in the endoplasmic reticulum (ER), which is able to sense cellular stress and trigger either rescue responses ...

Hereditary neurodegeneration linked to ADP-ribose modification

Attaching chains of the small molecule ADP-ribose to proteins is important for a cell's survival and the repair of DNA damage, making this process a promising target for the development of new cancer drugs. Researchers have ...

Controlling self-renewal of stem cells

(PhysOrg.com) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) are the first to establish a direct link between a conserved stem cell factor and the cell cycle regulation in adult stem cells. ...

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