Heating proteins to body temperature reveals new drug targets
Some proteins shift their shape when exposed to different temperatures, revealing previously unknown binding sites for medications, new research has found.
Some proteins shift their shape when exposed to different temperatures, revealing previously unknown binding sites for medications, new research has found.
Molecular & Computational biology
May 15, 2024
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57
A team of researchers at the Universities of Tübingen and Göttingen has found that certain minerals with characteristic shapes could indicate the activity of bacteria in hydrothermal vents—or black smokers—in the deep ...
Cell & Microbiology
May 15, 2024
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40
Photon-number distributions of various light sources have been studied extensively. However, little is known about the statistical distribution of electrons emitted under the effect of intense light.
Optics & Photonics
May 13, 2024
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739
In the process of firing ceramics, the appearance, structure and properties of ceramics are determined by raw materials and firing technology, so the study of raw materials and firing technology of ancient ceramics has always ...
Archaeology
May 6, 2024
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3
In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes ...
Biochemistry
May 3, 2024
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30
Sourdough is the oldest kind of leavened bread in recorded history, and people have been eating it for thousands of years. The components of creating a sourdough starter are very simple—flour and water. Mixing them produces ...
Cell & Microbiology
May 1, 2024
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35
By exploiting a smart learning algorithm that fuses two microscopy signals, University of Michigan researchers have accomplished high-resolution, efficient 3D chemical imaging for the first time at the one-nanometer scale. ...
Nanomaterials
Apr 30, 2024
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35
A new research study from Opto-Electronic Advances discusses tailoring electron vortex beams with customizable intensity patterns by electron diffraction holography.
Optics & Photonics
Apr 23, 2024
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33
A team at the University of Tokyo have constructed an improved mid-infrared microscope, enabling them to see the structures inside living bacteria at the nanometer scale. Mid-infrared microscopy is typically limited by its ...
Optics & Photonics
Apr 17, 2024
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72
Scientists have found a way to transform metal waste into a highly efficient catalyst to make hydrogen from water, a discovery that could make hydrogen production more sustainable.
Analytical Chemistry
Apr 16, 2024
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1079
An electron microscope is a type of microscope that uses a particle beam of electrons to illuminate a specimen and create a highly-magnified image. Electron microscopes have much greater resolving power than light microscopes that use electromagnetic radiation and can obtain much higher magnifications of up to 2 million times, while the best light microscopes are limited to magnifications of 2000 times. Both electron and light microscopes have resolution limitations, imposed by the wavelength of the radiation they use. The greater resolution and magnification of the electron microscope is because the wavelength of an electron; its de Broglie wavelength is much smaller than that of a photon of visible light.
The electron microscope uses electrostatic and electromagnetic lenses in forming the image by controlling the electron beam to focus it at a specific plane relative to the specimen. This manner is similar to how a light microscope uses glass lenses to focus light on or through a specimen to form an image.
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