DNA damage is occurring in our cells all the time due to external agents, such as exposure to sun, or internal agents, like reactive oxygen species. To detect and repair DNA lesions, cells have evolved DNA damage response. ...
Cell & Microbiology
Feb 27, 2019
0
4
Finding ways to improve the drug development process – which is currently costly, time-consuming and has an astronomically high failure rate – could have far-reaching benefits for health care and the economy. Researchers ...
Analytical Chemistry
Oct 25, 2018
0
35
People who fall sick with drug-resistant tuberculosis (TB) face daunting odds. Only about two in three survive the illness, unlike people with drug-sensitive TB, of whom more than 90 percent survive.
Molecular & Computational biology
Sep 17, 2018
0
15
Programming the body's immune system to attack cancer cells has had promising results for treating blood cancers such as lymphoma and leukemia. This tactic has proven more challenging for solid tumors such as breast or lung ...
Bio & Medicine
Jul 9, 2018
0
157
Biologists have long understood the various parts within the cell. But how these parts interact with and respond to each other is largely unknown.
Cell & Microbiology
Feb 12, 2018
0
684
A paper just published in Nature Biotechnology outlines a pioneering method of screening a person's diverse set of antibodies for rapid therapeutic discovery. Antibody proteins are an important part of the human immune system ...
Biotechnology
Jan 17, 2018
0
159
Scientists from Trinity College Dublin have gained key structural insights into the machinery employed by opportunistic, disease-causing bacteria, which may help chemists design new drugs to inhibit them.
Biochemistry
Aug 9, 2017
0
18
The immune system consists of a great variety of cell types fulfilling diverse tasks in monitoring tissue homeostasis to protect against pathogens and to remove damaged cells. To ensure the smooth, controlled function of ...
Biochemistry
Apr 25, 2017
0
9
New computer models from North Carolina State University show how a variant of a common protein involved in human immune response binds to the antiviral drug abacavir, causing a severe life-threatening reaction known as the ...
Biochemistry
Mar 9, 2017
0
17
Biochemists at The University of Texas at Arlington have demonstrated the mechanism behind how thiopurine drugs suppress immune response.
Biochemistry
Nov 24, 2016
0
21
