Telomeres are large nucleoproteins structures that cap the ends of chromosomes in eukaryotic cells. When a cell divides, a small portion of the telomere is lost due to the inherently incomplete process of genome replication. ...
Biotechnology
Apr 22, 2021
0
197
From cancer treatment to sunlight, radiation and toxins can severely damage DNA in both harmful and healthy cells. While the body has evolved to efficiently treat and restore damaged cells, the mechanisms that allow this ...
Molecular & Computational biology
Apr 15, 2021
0
150
When large forces act on a heavy beam, for example, in bridge construction, the beam will be slightly deformed. Calculating the relationship between forces, internal stresses and deformations is one of the standard tasks ...
Molecular & Computational biology
Aug 5, 2020
0
80
On the DNA assembly line, two proofreading proteins work together as an emergency stop button to prevent replication errors. New research from North Carolina State University and the University of North Carolina at Chapel ...
Cell & Microbiology
Jul 16, 2020
0
239
As chromosomes go, X and Y make an unlikely pair. The X is large and contains thousands of genes critical for life. The Y, by contrast, is little more than a nub. Its main purpose is to provide the instructions for initiating ...
Biotechnology
May 28, 2020
4
93
An interdisciplinary team of researchers at the Hong Kong University of Science and Technology (HKUST) unraveled how a toxin released by Escherichia coli (E. coli) – a human gut bacteria, is connected to colorectal cancer, ...
Biochemistry
Sep 17, 2019
0
89
Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient.
Biotechnology
Jul 11, 2018
0
526
One of the most potent toxins known acts by welding the two strands of the famous double helix together in a unique fashion which foils the standard repair mechanisms cells use to protect their DNA.
Biochemistry
Aug 2, 2017
0
138
Almost all life on Earth is based on DNA being copied, or replicated. Now for the first time scientists have been able to watch the replication of a single DNA molecule, with some surprising findings. For one thing, there's ...
Cell & Microbiology
Jun 15, 2017
15
81
In the early 1990s, Jacqueline Barton, the John G. Kirkwood and Arthur A. Noyes Professor of Chemistry at Caltech, discovered an unexpected property of DNA—that it can act like an electrical wire to transfer electrons quickly ...
Biochemistry
Feb 24, 2017
2
96
