Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have discovered how two important proofreader proteins know where to look for errors during DNA replication and how they ...
Cell & Microbiology
Aug 21, 2015
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(Phys.org)—Genome editing for purposes of replication and repair is handled by enzymes called endonucleases, which cleave DNA strands at very specific sites. These are called "restriction sites," composed of palendromic ...
Ludwig Maximilian University of Munich researchers have discovered a further function of the base-pairing that holds the two strands of the DNA double helix together: it plays a crucial role in protecting the DNA from the ...
Biochemistry
Sep 19, 2014
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A variety of cancers are treated with the anti-tumor agent bleomycin, though its disease-fighting properties remain poorly understood. In a new study, lead author Basab Roy—a researcher at Arizona State University's Biodesign ...
Biochemistry
Apr 30, 2014
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(Phys.org) —Maybe you've seen the movies or played with toy Transformers, those shape-shifting machines that morph in response to whatever challenge they face. It turns out that DNA-repair machines in your cells use a similar ...
Cell & Microbiology
Feb 3, 2014
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A research team from NPL and the University of Edinburgh have invented a new way to zip and unzip DNA strands using electrochemistry.
Biochemistry
Apr 18, 2013
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In a project that began with the retinal cells of nocturnal animals and has led to fundamental insights into the organization of genomic DNA, researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich show how the nuclear ...
Cell & Microbiology
Feb 1, 2013
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Every time a human or bacterial cell divides it first must copy its DNA. Specialized proteins unzip the intertwined DNA strands while others follow and build new strands, using the originals as templates. Whenever these proteins ...
Cell & Microbiology
Dec 13, 2012
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(Phys.org)—A research team in Italy has succeeded in capturing a high contrast image of a band of DNA fiber – the closest anyone has ever come to taking a photograph of a single strand of DNA. The team has outlined the ...
For the first time, researchers at the University of California, Davis, have watched single strands of DNA being prepped for repair. The research, published this week in the journal Nature, has implications for understanding ...
Cell & Microbiology
Oct 29, 2012
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