Smart chemistry rids anti-cancer drugs of serious side effects

Researchers of the Leiden University Medical Centre (LUMC) and the Leiden Institute of Chemistry have made an important discovery about the commonly used anti-cancer drug doxorubicin. They have found a way to reduce its side ...

Technique reveals how crystals form on surfaces

The process of crystallization, in which atoms or molecules line up in orderly arrays like soldiers in formation, is the basis for many of the materials that define modern life, including the silicon in microchips and solar ...

Scientists now know what DNA's chaperone looks like

It's long been known that the proteins that package DNA, like students at a high school dance, require a chaperone. But what exactly that guardian looks and acts like has been a mystery—until now.

Unraveling gene expression

The DNA of a single cell is two to three meters long end-to-end. To fit in the nucleus and function correctly, DNA is packaged around specialized proteins. These DNA-protein complexes are called nucleosomes, and they are ...

DNA replication machinery captured at atom-level detail

July 15, 2019) Life depends on double-stranded DNA unwinding and separating into single strands that can be copied for cell division. St. Jude Children's Research Hospital scientists have determined at atomic resolution the ...

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