From cancer treatment to sunlight, radiation and toxins can severely damage DNA in both harmful and healthy cells. While the body has evolved to efficiently treat and restore damaged cells, the mechanisms that allow this ...
Molecular & Computational biology
Apr 15, 2021
0
150
There are many ways in which the genetic material DNA can be damaged, resulting in the development of diseases such as cancer. Certain forms of DNA damage are associated with so-called R-loops. These are three-stranded structures ...
Molecular & Computational biology
Feb 8, 2022
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21
In order to react effectively to changes in the surroundings, bacteria must be able to quickly turn specific genes on or off. Although the overall mechanisms behind gene regulation have long been known, the fine details have ...
Cell & Microbiology
Nov 11, 2013
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0
It is a big dream in science: To start from scratch with simple artificial microskopic building blocks and end up with something much more complex: living systemts, novel computers or every-day materials. For decades scientists ...
Biochemistry
Feb 4, 2014
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0
The DNA genomes of organisms whose cells possess nuclei are packaged in a highly characteristic fashion. Most of the DNA is tightly wrapped around protein particles called nucleosomes, which are connected to each other by ...
Cell & Microbiology
Aug 20, 2010
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0
By studying the yeast used in beer- and bread-making, researchers at the University of Pittsburgh School of Medicine have uncovered the mechanism by which ancient proteins repair DNA damage and how their dysfunction could ...
Cell & Microbiology
Jul 28, 2015
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41
Scientists at The University of Nottingham have demonstrated for the first time that it is possible to selectively sequence fragments of DNA in real time, greatly reducing the time needed to analyse biological samples.
Biotechnology
Jul 25, 2016
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37
How to create nanocages, i.e., robust and stable objects with regular voids and tunable properties? Short segments of DNA molecules are perfect candidates for the controllable design of novel complex structures. Physicists ...
Bio & Medicine
Oct 18, 2018
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4
A research collaboration between the Medical University of South Carolina, the Institute of Human Genetics in France, and Howard Hughes Medical Institute at Rockefeller University has revealed the means by which cells accomplish ...
Cell & Microbiology
Jun 14, 2016
0
14
Joining computer simulations and lab experiments, an international research group sheds light on one of the key mechanisms of cell life.
Molecular & Computational biology
Oct 30, 2019
0
7
