It was like a map of New York missing all of Manhattan. The human reference genome finally has all its blank spots filled in, and seeing everything we missed the first time around is both repetitive—and enlightening.
Molecular & Computational biology
Mar 31, 2022
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293
Two remarkable discoveries were today revealed by researchers into genome analysis of Leishmania parasites. These results uncovered a surprising level of variation at the genome structure level.
Biotechnology
Oct 27, 2011
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0
Genetic variants that can act as switches directing structural changes in the RNA molecules that code for proteins in plants have been experimentally validated in plants for the first time. The changes to RNA structure can ...
Plants & Animals
Jun 14, 2022
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1110
DNA testing kits for humans and their pets are a growing business. The draw for consumers ranges from understanding why their dog looks like a Labrador but acts like a German Shepherd, or what diseases they might be prone ...
Plants & Animals
Feb 19, 2020
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10
The speed and error rate of DNA synthesis is influenced by the three-dimensional structure of the DNA. Using "third-generation" genome-wide DNA sequencing data, a team of researchers from Penn State and the Czech Academy ...
Biotechnology
Nov 13, 2018
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68
In species with sexual reproduction, no two individuals are alike, and scientists have long struggled to understand why there is so much genetic variation. In a new study published in Nature Ecology & Evolution, a team of ...
Evolution
Nov 18, 2019
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15
The term "single-nucleotide polymorphism" (SNP) refers to a single base change in DNA sequence between two individuals. SNPs are the most common type of genetic variation in plant and animal genomes and are, thus, an important ...
Biotechnology
Apr 1, 2015
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7
A new tool will help researchers identify the minute changes in DNA patterns that lead to cancer, Huntington's disease and a host of other genetic disorders. The tool was developed at North Carolina State University and translates ...
Cell & Microbiology
May 19, 2009
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0
Combining two emerging large-scale technologies for the first time—multiplexed mass spectrometry and a mouse population with a high level of natural genetic diversity —researchers at Harvard Medical School (HMS) and The ...
Cell & Microbiology
Jun 15, 2016
2
7
DNA sequences that can fold into shapes other than the classic double helix tend to have higher mutation rates than other regions in the human genome. New research by a team of Penn State scientists shows that the elevated ...
Molecular & Computational biology
Feb 8, 2021
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