A team of Penn State scientists has shed light on the processes that lead to certain human DNA mutations that are implicated in hundreds of inherited diseases such as tuberous sclerosis and neurofibromatosis type 1. The ...
Cell & Microbiology
Jul 2, 2009
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A typical human cell contains hundreds of mitochondria—energy-producing organelles—that continually fuse and divide. Relatively little is known, however, about why mitochondria undergo this behavior.
Cell & Microbiology
Apr 15, 2010
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When bacteria are exposed to antibiotics, they alter the expression of a number of genes within their genome. One of these responses, known as the SOS response, results in an increase in the rate of DNA mutation. Given that ...
Cell & Microbiology
Oct 7, 2015
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52
New mutations occur at increasing rates in the mitochondrial genomes of developing egg cells in aging rhesus monkeys, but the increases appear to plateau at a certain age and are not as large as those seen in non-reproductive ...
Molecular & Computational biology
Apr 4, 2022
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252
Scientists have long held theories about the importance of proteins called B-type lamins in the process of embryonic stem cells replicating and differentiating into different varieties of cells. New research from a team led ...
Cell & Microbiology
Nov 24, 2011
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It is well established that folic acid supplementation can significantly reduce the risk of birth defects, including neural tube defects like spina bifida, the most common birth defect of the central nervous system and the ...
Cell & Microbiology
Mar 6, 2023
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12
Whilst most organisms try to stop their DNA from mutating, scientists from the UK and China have discovered that a common fungus found on bread actively mutates its own DNA as a way of fighting virus-like infections.
Biotechnology
Jun 22, 2020
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112
To make the iconic, twisted double helix that accounts for the diversity of life, DNA rules specify that G always pairs with C, and A with T.
Evolution
Jan 3, 2018
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208
A team of researchers from Colorado State University has been studying DNA damage in living cells to learn more about how genetic abnormalities arise. It has long been known that DNA molecules in every cell get constantly ...
Cell & Microbiology
Dec 21, 2015
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26
Reducing naturally occurring errors in protein synthesis (production) improves both health and lifespan, finds a new study in simple model organisms led by researchers at UCL and MRC London Institute of Medical Sciences.
Cell & Microbiology
Sep 14, 2021
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