Mount Sinai researchers have discovered how the enzyme DNA polymerase delta works to duplicate the genome that cells hand down from one generation to the next. In a study published in Nature Structural & Molecular Biology, ...
Molecular & Computational biology
Oct 3, 2019
0
397
Epigenetic regulation of gene expression is associated with switching between chromatin states characterized by distinct histone modifications.
Cell & Microbiology
Jun 30, 2020
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120
For the first time, scientists have used large-scale DNA sequencing data to investigate a long-standing evolutionary assumption: DNA mutation rates are influenced by a set of species-specific life-history traits. These traits ...
Evolution
Jun 13, 2011
1
0
The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability of transfer RNA (tRNA) molecules to couple recognition of the genetic ...
Molecular & Computational biology
Oct 19, 2018
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29
The "sloppier copier" discovered by USC biologists is also the best sixth man in the DNA repair game, an article in the journal Nature shows.
Cell & Microbiology
Jul 15, 2009
3
0
Adaptations to environmental change are the most important asset for the persistence of any plant or animal species. This is usually achieved through genetic mutation and selection, a slow process driven by chance. Faster ...
Plants & Animals
Dec 28, 2018
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43
There was no hanky-panky involved when a fairy-tale white foal was born to two brown Standardbreds at the Four Winds Farm in New Jersey. DNA tests confirm that the snowy foal, born May 6, is a mutant, but that's nothing to ...
Plants & Animals
Jun 1, 2012
2
0
Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities. ...
Bio & Medicine
Jan 27, 2021
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94
Exposure to mutagens, or mutation-causing agents, can not only bring about changes in DNA but also appear to induce errors when genes are transcribed to make proteins, which may be an important factor in age-related diseases.
Biotechnology
Dec 21, 2020
0
41
Plants adapt to the local weather and soil conditions in which they grow, and these environmental adaptations are known to evolve over thousands of years as mutations slowly accumulate in plants' genetic code. But a University ...
Biotechnology
May 3, 2011
2
0
