The genetic information we receive from our parents in the form of chromosomes are mosaics assembled from the two copies of chromosomes each parent has. How such cuts—or breaks—in our genetic material are repaired is ...
Cell & Microbiology
Apr 7, 2016
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A group of researchers led by Tomoji Mashimo, Associate Professor, Institute of Experimental Animal Sciences, Graduate School of Medicine, Osaka University and Kazuto Yoshitomi, Assistant Professor, Mouse Genomics Resource ...
Biotechnology
Mar 24, 2016
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2
The genome of developing brain cells harbors 27 clusters or hotspots where its DNA is much more likely to break in some places than others, researchers from the Program in Cellular and Molecular Medicine (PCMM) at Boston ...
Biotechnology
Feb 11, 2016
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1103
A streamlined protocol for an alternative gene insertion method using genome editing technologies, the PITCh (Precise Integration into Target Chromosome) system, has been reported in Nature Protocols by Specially Appointed ...
Biotechnology
Dec 17, 2015
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5
Sometimes, the molecules that make up life exhibit strange behavior. For instance, in simple organisms such as yeast, when genetic material becomes damaged, the affected DNA strands increase their motion, waving about inside ...
Cell & Microbiology
Nov 5, 2015
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Every organism—from a seedling to a president—must protect its DNA at all costs, but precisely how a cell distinguishes between damage to its own DNA and the foreign DNA of an invading virus has remained a mystery.
Cell & Microbiology
Aug 27, 2015
3
77
Leveraging a novel system designed to examine the double-strand DNA breaks that occur as a consequence of gene amplification during DNA replication, Whitehead Institute scientists are bringing new clarity to the causes of ...
Biotechnology
Jun 4, 2015
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17
Scientists from A*STAR's Bioinformatics Institute (BII) have developed an analytical model and computational tool to rapidly and accurately predict the occurrence and locations of R-loop Forming Sequences (RLFSs) in any genome ...
Biotechnology
May 29, 2015
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22
Some bacteria are able to thrive even when under continued attack, scientists have found, in a development that may help explain how our immune systems can't always prevent infections.
Cell & Microbiology
Oct 29, 2014
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2
(Phys.org) —Yale University researchers have determined how a scarce molecule produced by marine bacteria can kill cancer cells, paving the way for the development of new, low-dose chemotherapies.
Biochemistry
May 12, 2014
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