Gene activity database could spare thousands of mice

A comprehensive database of gene activity in mice across ten disease models, which could significantly reduce animal use worldwide, has been developed by scientists at the Francis Crick Institute, which gives a full picture ...

'Cannibalism' is a double-whammy for cell health

Certain Inflammatory and infectious diseases, such as hardening arteries and tuberculosis, are caused by the build-up inside immune cells of harmful substances, such as cholesterol and bacteria. A study published today by ...

Next-generation single-dose antidotes for opioid overdoses

The U.S. opioid epidemic is being driven by an unprecedented surge in deaths from fentanyl and other synthetic opiates. Fentanyl's powerful effects are long-lasting, and even tiny amounts of the drug can lead to an overdose. ...

Team develops first genetic switch for C. elegans

With their first ever RNA-based inducible system for switching on genes in the roundworm Caenorhabditis elegans (C. elegans), two researchers from the University of Konstanz have closed a significant gap in genetic switches. ...

Why it's difficult to predict evolutionary fate of a new trait

The phrase "survival of the fittest" makes the principle of evolution by natural selection easy to understand—individuals with a trait that adapts them well to their circumstances are more likely to pass that trait along. ...

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