Active genetics technology opens new horizons

In 2015, University of California San Diego biologists Ethan Bier and Valentino Gantz developed a breakthrough technology known as "active genetics," which results in parents transmitting a genetic trait to most of their ...

A hair-trigger for cells fighting infection

To fight infections cells in the immune system play a dangerous game with their own genes. Damaging genes allows B cells to make antibodies that are specifically equipped to target to specific causes of illness, but damaging ...

Microbes seen controlling action of host's genes

All animals—from sea sponges to modern-day humans—evolved in a world already teeming with microbes. These single-celled microorganisms now cover practically every surface of our bodies and are as much a part of our biology ...

Overcoming hurdles in CRISPR gene editing to improve treatment

More and more scientists are using the powerful new gene-editing tool known as CRISPR/Cas9, a technology isolated from bacteria, that holds promise for new treatment of such genetic diseases as cystic fibrosis, muscular dystrophy ...

Precaution and governance of emerging technologies

Precautionary approaches to governance of emerging technology, which call for constraints on the use of technology whose potential harms and other outcomes are highly uncertain, are often criticized for reflecting "risk panics," ...

Reading the rules of gene regulation with CRISPR

We have barely begun to crack open the rulebook for the vast noncoding regions of the genome. Two new methods, building on CRISPR advances, may help reveal some of the pages.

Using light to control genome editing

The genome-editing system known as CRISPR allows scientists to delete or replace any target gene in a living cell. MIT researchers have now added an extra layer of control over when and where this gene editing occurs, by ...

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