Scientists at the University of Massachusetts Medical School (UMMS) have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication. This work, led by Abraham Brass, MD, PhD, assistant ...
Cell & Microbiology
Jun 21, 2016
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Harvard Medical School scientists have found a compound that in laboratory dishes blocks the dengue virus in two ways, raising hopes for a future drug whose dual activity could suppress the otherwise likely emergence of drug ...
Cell & Microbiology
Apr 22, 2016
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Mosquitoes are a key contributor to the spread of potentially deadly diseases such as dengue and malaria, as they harbor parasites and viruses that are spread when mosquitoes bite humans and animals. Now, researchers at the ...
Biotechnology
Sep 3, 2015
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Diseases transmitted by mosquitoes have contributed to the death and suffering of millions throughout human history, earning the mosquito the title as the world's most dangerous animal. Even today, several devastating mosquito-borne ...
Cell & Microbiology
Jan 20, 2015
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It's a dry winter day in southeast Brazil, but a steamy tropical summer reigns inside the labs at Oxitec, where workers are making an unusual product: genetically modified mosquitoes to fight dengue fever.
Biotechnology
Aug 27, 2014
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Dengue fever and West Nile fever are mosquito-borne diseases that affect hundreds of millions of people worldwide each year, but there is no vaccine against either of the related viruses.
Cell & Microbiology
Feb 6, 2014
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(Phys.org) —Biting mosquitoes are not only annoying but can be dangerous, even deadly. A new study involving researchers at the University of Notre Dame explores a potential biological mechanism through which disease virus ...
Cell & Microbiology
Aug 26, 2013
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(Phys.org) —Scientists have revealed a new technique to introduce disease-blocking bacteria into mosquitoes, with promising results that may halt the spread of diseases such as dengue, yellow fever and potentially malaria.
Cell & Microbiology
Apr 10, 2013
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Researchers have identified enzymes and biochemical compounds called lipids that are targeted and modified by the dengue virus during infection, suggesting a potential new approach to control the aggressive mosquito-borne ...
Cell & Microbiology
Mar 22, 2012
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Scientists have determined the structure of the enzyme endomannosidase, significantly advancing our understanding of how a group of devastating human viruses including HIV and Hepatitis C hijack human enzymes to reproduce ...
Biochemistry
Jan 4, 2012
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