Gene invaders are stymied by a cell's genome defense

Gene wars rage inside our cells, with invading DNA regularly threatening to subvert our human blueprint. Now, building on Nobel-Prize-winning findings, UC San Francisco researchers have discovered a molecular machine that ...

Architecture of rod sensory cilium disrupted by mutation

Using a new technique called cryo-electron tomography, two research teams at Baylor College of Medicine have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium ...

Why does eczema often lead to asthma?

Many young children who get a severe skin rash develop asthma months or years later. Doctors call the progression from eczema, or atopic dermatitis, to breathing problems the atopic march. In this week's issue of PLoS Biology, ...

Tissue mechanics essential for cell movement

Cells that form facial features need surrounding embryonic tissues to stiffen so they can move and develop, according to new UCL-led research.

Understanding congenital heart defects, one chicken at a time

Approximately 10 percent of infants are born with a congenital heart defect, with one of the most common being persistent truncus arteriosus—a hole in the heart. In a healthy baby, deoxygenated blood is pumped through a ...

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