Fishing for proteins: Scientists use new optical tweezer technology to study DNA repair
Tucked away in a small, dark room at UPMC Hillman Cancer Center, Brittani Schnable is on a fishing expedition.
Tucked away in a small, dark room at UPMC Hillman Cancer Center, Brittani Schnable is on a fishing expedition.
Biotechnology
Mar 1, 2023
0
88
Whether radiation exposure of fathers can have consequences on their children is one of the most long-standing questions in radiation biology. Using the nematode Caenorhabditis elegans as a model, Professor Dr. Björn Schumacher ...
Molecular & Computational biology
Dec 21, 2022
0
33
Scientists from the group of Professor Dr. Thorsten Hoppe at the Cologne Cluster of Excellence for Aging Research CECAD have found that in the nematode C. elegans, the perception of changes in ambient temperature via a defined ...
Cell & Microbiology
Oct 7, 2022
0
10
In times of war, factories retool to support the needs of battle. Assembly lines change course from turning out car parts to machine guns, or from building washing machines to aircraft engines.
Plants & Animals
Aug 25, 2022
0
393
City College of New York associate professor of physics Ronald Koder and his team at the Koder Lab are advancing the field of molecular detection by developing the first proteins that can detect a deadly nerve agent called ...
Biochemistry
Jul 6, 2022
1
90
DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.
Molecular & Computational biology
Mar 21, 2022
0
73
Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects ...
Cell & Microbiology
Dec 28, 2021
0
254
Many of the processes that keep us alive also put us at risk. The energy-producing chemical reactions in our cells, for example, also produce free radicals—unstable molecules that steal electrons from other molecules. When ...
Cell & Microbiology
Nov 4, 2021
0
555
About 95% of all crystal structures obtained for various proteins and deposited in public databases are captured using cryogenic technology. This technology requires frozen conditions. Scientists at St. Jude Children's Research ...
Biochemistry
Aug 19, 2021
0
419
A research team from Cologne has discovered that a change in the DNA structure—more precisely in the chromatin—plays a decisive role in the recovery phase after DNA damage. The key is a double occupation by two methyl ...
Cell & Microbiology
Oct 13, 2020
0
283