One drug, many diseases

It seems too good to be true: a single drug that could treat humanity's worst afflictions, including atherosclerosis, cancer, Alzheimer's, Parkinson's and arthritis. All of these diseases have one thing in common—they involve ...

Laser pulses reveal DNA repair mechanisms

A new straightforward method enables monitoring the response of nuclear proteins to DNA damage in time and space. The approach is based on nonlinear photoperturbation.

Mayo researchers find off/on switch for DNA repair protein

Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now, in a new paper published in Nature Structural & Molecular Biology, Mayo researchers have determined how one DNA repair protein gets ...

A chaperone for the 'guardian of the genome'

The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, ...

Team creates first ever VX neurotoxin detector

City College of New York associate professor of physics Ronald Koder and his team at the Koder Lab are advancing the field of molecular detection by developing the first proteins that can detect a deadly nerve agent called ...

Packaging and unpacking of the genome

DNA represents a dynamic form of information, balancing efficient storage and access requirements. Packaging approximately 1.8m of DNA into something as small as a cell nucleus is no mean feat, but unpacking it again to access ...

Frog eggs help researchers understand repair of DNA damages

The DNA replication process in which cells divide to create new cells also triggers repair of DNA damage, researchers from the University of Copenhagen report in a new study. The researchers studied extracts from frog eggs, ...

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