Oleoyl-LPE exerts neurite stimulation and neuroprotection

Lysophospholipids are phospholipids that have just one fatty acid chain, and in recent years, the role of lysophospholipids in physiology and pathophysiology has attracted attention. Lysophosphatidylethanolamine (LPE) is ...

Measuring the hardness of living tissues without damage

When a fertilized egg is developing into a fetus, cell populations forming tissues are in a fluid state, and thus, the tissue can be easily deformed. Cells also generate mechanical forces during development that contribute ...

Plants fix DNA differently from animals

In mammalian cells, the transcription factor p53 most responsible for healthy growth of the organism. The equivalent in plants is Suppressor Of Gamma Response 1 (SOG1), a factor that does not share a common evolutionary ancestor ...

One, two, four, eight – lessons from dividing cells

The IMCB was established in 1987 at the National University of Singapore before becoming an autonomous research institute of A*STAR and moving to Biopolis in 2004. The IMCB strives to maintain the scientific excellence of ...

What are the mechanisms of zooxanthella expulsion from coral?

Coral bleaching, which often results in the mass mortality of corals and in the collapse of coral reef ecosystems, has become an important issue around the world, with the number of coral reefs decreasing annually.

Observing how EGFR clusters malfunction in cancer cells

For scientists to improve cancer treatments with targeted therapeutic drugs, they need to be able to see proteins prevalent in the cancer cells. This has been an impossible, until now. Thanks to a new microscopy technique, ...

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