New sequencing method uses nanopores to detect DNA damage

Scientists worldwide are racing to sequence DNA – decipher genetic blueprints – faster and cheaper than ever by passing strands of the genetic material through molecule-sized pores. Now, University of Utah scientists ...

DNA and the 'magic rings' trick

(PhysOrg.com) -- A new study from UC Davis shows how, like a conjuring trick with interlocking rings, two interlocked pieces of DNA are separated after DNA is copied or repaired. The finding was published online Oct. 10 in ...

Chromosome 'glue' surprises scientists

Proteins called cohesins ensure that newly copied chromosomes bind together, separate correctly during cell division, and are repaired efficiently after DNA damage. Scientists at the Carnegie Institution have found for the ...

Key protein aids in DNA repair

Scientists have shown in multiple contexts that DNA damage over our lifetimes is a key mechanism behind the development of cancer and other age-related diseases. Not everyone gets these diseases, because the body has multiple ...

Nanoparticles may cause DNA damage across a cellular barrier

(PhysOrg.com) -- Scientists have shown in the laboratory that metal nanoparticles damaged the DNA in cells on the other side of a cellular barrier. The research, by the University of Bristol, is published online this week ...

New study overturns orthodoxy on how macrophages kill bacteria

For decades, microbiologists assumed that macrophages, immune cells that can engulf and poison bacteria and other pathogens, killed microbes by damaging their DNA. A new study from the University of Illinois disproves that.

What's in your water?: Disinfectants create toxic by-products

Although perhaps the greatest public health achievement of the 20th century was the disinfection of water, a recent study now shows that the chemicals used to purify the water we drink and use in swimming pools react with ...

New step in DNA damage response in neurons discovered

Researchers have identified a biochemical switch required for nerve cells to respond to DNA damage. The finding, scheduled for advance online publication in Nature Cell Biology, illuminates a connection between proteins involved ...

Researchers uncover human DNA repair by nuclear metamorphosis

Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.

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