Scientists have known for a long time that when DNA is damaged, a key enzyme sets off a cellular "alarm bell" to alert the cell to start the repair process, but until recently little was known about how the cell detects and ...
Cell & Microbiology
Aug 13, 2009
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Researchers at Washington University School of Medicine in St. Louis have shed new light on a process that fixes breaks in the genetic material of the body's cells. Their findings could lead to ways of enhancing chemotherapy ...
Cell & Microbiology
Jul 16, 2009
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(PhysOrg.com) -- Penny Beuning, an assistant professor of chemical biology and biotechnology at Northeastern, this month received a National Science Foundation (NSF) Faculty Early-Career Development grant to study how cells ...
Biochemistry
Jul 15, 2009
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When cells experiencing DNA damage fail to repair themselves, they send a signal to their neighbors letting them know they're in trouble. The discovery, which shows that a process dubbed the DDR (DNA Damage Response) also ...
Cell & Microbiology
Jul 13, 2009
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Mycobacterium tuberculosis is arguably the world's most successful infectious agent because it knows how to avoid elimination by slowing its own growth to a crawl. Now, a report in the July 10 issue of the journal Cell, a ...
Cell & Microbiology
Jul 9, 2009
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(PhysOrg.com) -- Every day people are exposed to chemical and physical agents that damage DNA. If it isn't repaired properly, this damage can lead to mutations that in some circumstances can lead to the development of cancer ...
Biotechnology
Jun 29, 2009
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Like a mechanic popping the hood of a car to get at a faulty engine, a tumor-suppressing protein allows cellular repair mechanisms to pounce on damaged DNA by overcoming a barrier to DNA access.
Cell & Microbiology
Jun 19, 2009
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Those pesky graying hairs that tend to crop up with age really are signs of stress, reveals a new report in the June 12 issue of Cell.
Cell & Microbiology
Jun 11, 2009
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Some DNA repair enzymes can become double-edged swords - If they work too slowly, they can block necessary cell maintenance and contribute to cell death. This could explain the somewhat mysterious success of the widely used ...
Cell & Microbiology
Apr 28, 2009
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For decades, microbiologists assumed that macrophages, immune cells that can engulf and poison bacteria and other pathogens, killed microbes by damaging their DNA. A new study from the University of Illinois disproves that.
Cell & Microbiology
Apr 27, 2009
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