Cryo-electron microscopy by University of Alabama at Birmingham researchers has exposed the structure of a bacterial virus with unprecedented detail. This is the first structure of a virus able to infect Staphylococcus epidermidis, ...
Molecular & Computational biology
Dec 16, 2022
0
147
CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases. However, there is a last-mile problem—these tools need to be effectively ...
Biotechnology
May 26, 2022
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282
Using 3-D electron microscopy, structural biologists from the University of Zurich succeeded in elucidating the architecture of the lamina of the cell nucleus at molecular resolution for the first time. This scaffold stabilizes ...
Biochemistry
Mar 1, 2017
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713
(Phys.org) —A team of researchers working at the Chinese Academy of Sciences, in Beijing, has used cryo-electron microscopy to reveal how it is that DNA wraps so tightly around nuclesomes. In their paper published in the ...
Most of the cells in our bodies—be they bone, muscle or pancreas cells—are locked into the right place with the help of tiny anchors (called 'focal adhesions'). These strong anchors use protein chains to link the cell ...
Cell & Microbiology
Sep 13, 2021
0
632
DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a study from researchers at Weill Cornell Medicine and the National Heart, Lung, and Blood Institute, part of the National ...
Molecular & Computational biology
Jun 21, 2023
0
288
The RNA molecule is commonly recognized as messenger between DNA and protein, but it can also be folded into intricate molecular machines. An example of a naturally occurring RNA machine is the ribosome, that functions as ...
Bio & Medicine
Feb 27, 2023
0
114
A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in near-atomic detail, the architecture of a metabolic enzyme bound to a drug that blocks its activity. ...
General Physics
May 7, 2015
0
56
A gene that has been associated with severe learning disabilities in humans has been found to also play a vital role in cells' response to environmental stress, according to a Duke University study appearing May 24 in the ...
Cell & Microbiology
May 27, 2022
1
109
The scientists who received the 2017 Nobel Prize in chemistry were honored for their development of a technique called cryo-electron microscopy, or cryo-EM. The technology was revolutionary because it enabled scientists to ...
Analytical Chemistry
Sep 27, 2023
0
99
