Cross-coupling ketones: Adding flexibility to the synthetic chemistry toolbox
Researchers have published a paper describing, for the first time, the use of ketones as alkyl cross-coupling synthons.
Researchers have published a paper describing, for the first time, the use of ketones as alkyl cross-coupling synthons.
Biochemistry
May 30, 2022
0
90
Light-emitting diodes (LEDs) are commonly used in the electronic displays in our TVs, smartphones, and other devices; now, researchers at the Institute of Chemical Reaction Design and Discovery (ICReDD) at Hokkaido University ...
Materials Science
Jan 18, 2022
0
111
If there were a classroom full of all the transition metals that could be used as catalysts for complex pharmaceutical reactions, iron would be the most promising but most unruly member.
Materials Science
Oct 25, 2021
0
76
Metal catalysts are widely used in the production of drugs, dyes, adhesives, and plastics. Researchers have now discovered an intriguing property of nickel as a catalyst: it is able to catalyze the coupling of aromatic hydrocarbons ...
Materials Science
Oct 20, 2021
0
52
Scientists from Hokkaido University have developed a rapid, efficient protocol for cross-coupling reactions, vastly expanding the pool of chemicals that can be used for the synthesis of useful organic compounds.
Materials Science
May 18, 2021
1
15
Negishi cross-coupling reactions have been widely used to form C-C bonds since the 1970s and are often perceived as the result of two metals, zinc and palladium/nickel, working in synergy. But like all relationships, there ...
Materials Science
Feb 8, 2021
0
40
A trio of chemists at Okayama University has published a paper in the journal Nature Catalysis outlining the manner in which sodium can be safely used for cross-coupling reactions. In their paper, Sobi Asako, Hirotaka Nakajima ...
A cross-coupling reaction is typically performed in an organic solvent and leads to the production of a large amount of solvent waste, which is often harmful to the environment. A new strategy developed by Hokkaido University ...
Materials Science
Feb 8, 2019
0
60
Green chemistry is akin to baking. Both require precision and specific ingredients to produce the desired results. The trick is figuring out exactly which ingredients to use, and in what combinations.
Materials Science
Sep 22, 2015
0
415
The continued development of pharmaceuticals depends on the ability to form a wide range of chemical bonds. Diaryl ethers, characterized by the presence of an oxygen atom connected to two aryl groups, are a class of organic ...
Materials Science
Mar 28, 2022
0
23