Cross-coupling ketones: Adding flexibility to the synthetic chemistry toolbox
Researchers have published a paper describing, for the first time, the use of ketones as alkyl cross-coupling synthons.
Researchers have published a paper describing, for the first time, the use of ketones as alkyl cross-coupling synthons.
Biochemistry
May 30, 2022
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90
The continued development of pharmaceuticals depends on the ability to form a wide range of chemical bonds. Diaryl ethers, characterized by the presence of an oxygen atom connected to two aryl groups, are a class of organic ...
Materials Science
Mar 28, 2022
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23
Light-emitting diodes (LEDs) are commonly used in the electronic displays in our TVs, smartphones, and other devices; now, researchers at the Institute of Chemical Reaction Design and Discovery (ICReDD) at Hokkaido University ...
Materials Science
Jan 18, 2022
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111
If there were a classroom full of all the transition metals that could be used as catalysts for complex pharmaceutical reactions, iron would be the most promising but most unruly member.
Materials Science
Oct 25, 2021
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76
Metal catalysts are widely used in the production of drugs, dyes, adhesives, and plastics. Researchers have now discovered an intriguing property of nickel as a catalyst: it is able to catalyze the coupling of aromatic hydrocarbons ...
Materials Science
Oct 20, 2021
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52
Scientists from Hokkaido University have developed a rapid, efficient protocol for cross-coupling reactions, vastly expanding the pool of chemicals that can be used for the synthesis of useful organic compounds.
Materials Science
May 18, 2021
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15
Negishi cross-coupling reactions have been widely used to form C-C bonds since the 1970s and are often perceived as the result of two metals, zinc and palladium/nickel, working in synergy. But like all relationships, there ...
Materials Science
Feb 8, 2021
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40
Many production facilities (e.g. plastic manufacturers, pharma companies, and others) use nanocatalysts that contain palladium—an expensive component that is not sustainably produced. A chemist from RUDN University found ...
Materials Science
Sep 4, 2020
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9
Acyl fluorides are organic compounds that contain a fluorine atom in their structure. These compounds have recently gained much attention in transition-metal catalysis due to their stability and selective reactivity. However, ...
Materials Science
Apr 9, 2020
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8
Azulene is a pretty neat substance. As the name suggests, it displays a peculiar blue color. First synthesized in the 1930s, azulene has been used in medicine for its bioactive properties. Now azulene derivatives are being ...
Materials Science
Feb 6, 2020
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10