Toward overcoming solubility issues in organic chemistry

Scientists from Hokkaido University have developed a rapid, efficient protocol for cross-coupling reactions, vastly expanding the pool of chemicals that can be used for the synthesis of useful organic compounds.

Understanding catalytic couplings: not all synergies are simple

Negishi cross-coupling reactions have been widely used to form C-C bonds since the 1970s and are often perceived as the result of two metals, zinc and palladium/nickel, working in synergy. But like all relationships, there ...

A green catalyst for pharmaceutical and industrial chemistry

Many production facilities (e.g. plastic manufacturers, pharma companies, and others) use nanocatalysts that contain palladium—an expensive component that is not sustainably produced. A chemist from RUDN University found ...

Boosting solid state chemical reactions

A cross-coupling reaction is typically performed in an organic solvent and leads to the production of a large amount of solvent waste, which is often harmful to the environment. A new strategy developed by Hokkaido University ...

Breaking reactivity barriers

The scope and productivity of an essential palladium-catalyzed coupling reaction that generates complex molecules has been improved thanks to A*STAR research that uses low-reactivity materials.

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