Michael Gross, professor of chemistry in Arts & Sciences at Washington University in St. Louis and of immunology and internal medicine at the School of Medicine, and his team are experts in footprinting proteins—that is, ...
Molecular & Computational biology
Dec 7, 2020
0
50
Noonan syndrome (NS) and Noonan syndrome with multiple lentigines (NS-ML) are rare human developmental disorders caused by mutations of the protein SHP2. Until recently, the mechanism of NS and NS-ML pathogenesis had been ...
Molecular & Computational biology
Oct 1, 2020
0
8
Mitochondria are the powerhouses of our cells, generating energy that supports life. A giant molecular proton pump, called complex I, is crucial: It sets in motion a chain of reactions, creating a proton gradient that powers ...
Cell & Microbiology
Sep 24, 2020
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425
The anti-de Sitter/conformal field theory (AdS/CFT) correspondence, also referred to as gauge/gravity duality, hypothesizes the existence of a relationship between two types of physics theories, namely gravity theories in ...
Human cells sense and communicate via cell surface receptors. Information about the environment is relayed to the inside of the cell through dynamic changes in their arrangement or conformation. To gain better understanding ...
Plants & Animals
Jun 23, 2020
0
3
A novel method to predict the most promising targets for antiviral drugs or vaccines is based on the conformational changes viral glycoproteins go through during the process of recognition and binding to the host cell. This ...
Molecular & Computational biology
Apr 20, 2020
0
5
Computational chemist Mahmoud Moradi will develop enhanced, 3-D simulations of the molecular dynamics of coronavirus spike glycoproteins to gain better understanding of how the virus binds to human cells.
Biochemistry
Apr 15, 2020
0
11
University of Groningen scientists have observed the characteristics of a single enzyme inside a nanopore. They learned that the enzyme can exist in four different folded states, or conformers, that play an active role in ...
Biochemistry
Apr 6, 2020
0
27
Mason Youngblood, a psychologist at City University of New York, has found a way to study cultural conformity bias in groups of people by studying music sampling used on commercially sold songs. In his paper published in ...
Ribosomes, the essential machinery used for protein synthesis is recycled after each one round of translation. An enzyme called ABCE1 is responsible for this process and turns out to be remarkably plastic as LMU biophysicists ...
Cell & Microbiology
Jul 18, 2019
0
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