Tubulin inhibitor with a unique molecular mechanism of action

Researchers at the Paul Scherrer Institute PSI and the Italian Institute of Technology IIT have developed a novel substance that disables a protein in the cell skeleton, leading to cell death. In this way, substances of this ...

A remote control for gene transfer

The ability to insert desirable genes into animal or human cells is the basis of modern life science research and of widespread biomedical applications. The methods used to date for this purpose are mostly non-specific, making ...

Breast cancer-on-a-chip for testing immunotherapy drugs

There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called 'checkpoint proteins.' These ...

Experimental evolution reveals how bacteria gain drug resistance

A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in experimentally evolving the common bacteria Escherichia coli under pressure from a large number of individual antibiotics. ...

New analysis method can lead to better cancer drugs

While proteins on the surfaces of cells are the targets for most drugs, refined methods are needed to analyze how these membrane proteins are organized. Researchers at Karolinska Institutet have developed a new DNA-based ...

page 3 from 6