Researchers identify drug compounds that can reduce prion protein levels in infected cells
Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins.
Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins.
Biochemistry
12 hours ago
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1
Safe and high-quality fertility preservation is of growing significance for women in clinical trials. Current primary methods for cryopreserving human oocytes are slow freezing and vitrification, but existing techniques pose ...
Bio & Medicine
15 hours ago
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1
In a recent study published in the journal Science Bulletin, researchers from the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University utilized hopping probe scanning ion conductance microscopy (HPICM) and highly ...
Bio & Medicine
May 13, 2024
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20
Mayflies live for only a day. Galapagos tortoises can reach up to age 170. The Greenland shark holds the world record at over 400 years of life.
Biotechnology
8 hours ago
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1
In clinical trials are conducted to allow safety and efficacy data to be collected for new drugs or devices. These trials can only take place once satisfactory information has been gathered on the quality of the product and its non-clinical safety, and Health Authority/Ethics Committee approval is granted in the country where the trial is taking place.
Depending on the type of product and the stage of its development, investigators enroll healthy volunteers and/or patients into small pilot studies initially, followed by larger scale studies in patients that often compare the new product with the currently prescribed treatment. As positive safety and efficacy data are gathered, the number of patients is typically increased. Clinical trials can vary in size from a single center in one country to multicenter trials in multiple countries.
Due to the sizable cost a full series of clinical trials may incur, the burden of paying for all the necessary people and services is usually borne by the sponsor who may be the pharmaceutical or biotechnology company that developed the agent under study. Since the diversity of roles may exceed resources of the sponsor, often a clinical trial is managed by an outsourced partner such as a contract research organization
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