A group of researchers at the University of California, Berkeley have for the first time described the structure of the active site core of topoisomerase II alpha, an important target for anti-cancer drugs.
Cell & Microbiology
Nov 15, 2012
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(PhysOrg.com) -- Biologist Barbara Mellone uses tiny cameras to study what happens when a dividing cell makes a mistake.
Cell & Microbiology
Sep 20, 2010
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If you can imagine identical twin sisters at rest, their breath drawing them subtly together and apart, who somehow latch onto ropes that pull them to opposite sides of the bed -- you can imagine what happens to a chromosome ...
Cell & Microbiology
Mar 10, 2010
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The Stowers Institute's Gerton Lab has provided new evidence to clarify the structure of nucleosomes containing Cse4, a centromere-specific histone protein required for proper kinetochore function, which plays a critical ...
Cell & Microbiology
Sep 28, 2009
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Lars Jansen's work on the formation of the centromere, a key cellular structure in powering and controlling chromosome segregation and accurate cell division, has just earned him a paper in Nature Cell Biology and a prestigious ...
Cell & Microbiology
Jul 1, 2009
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About 85-90 per cent of the cancer cells have the wrong number of chromosomes. But how do they survive and develop under these conditions? WWTF-"Young Investigator" Christopher Campbell and his team will trace the basic causes ...
Cell & Microbiology
Aug 31, 2015
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Researchers at the Cell Cycle Research Group of the Bellvitge Institute of Biomedical Research (IDIBELL) led by Ethel Queralt have reported in the journal PLoS Genetics an article which delve into the regulator mechanisms ...
Biotechnology
Dec 11, 2013
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