Researchers have discovered key mechanisms and structural details of a fundamental biological process—how a cell nucleus and its chromosomal material reorganizes itself after cell division. The new findings in chromosomal ...
Cell & Microbiology
Dec 4, 2019
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140
How, where and when genes are expressed determine individual phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls them? And how does genetic variation affect them? The SysGenetiX ...
Molecular & Computational biology
May 2, 2019
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91
What if we could program living cells to do what we would like them to do in the body? Having such control—a major goal of synthetic biology—could allow for the development of cell-based therapies that might one day replace ...
Biotechnology
Mar 14, 2016
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50
(Phys.org)—An interdisciplinary effort at the Friedrich Miescher Institute for Biomedical Research (FMI) addressed the question of how mRNA content, which is translated into proteins, is regulated in the cell. Supported ...
Cell & Microbiology
Sep 7, 2012
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0
(PhysOrg.com) -- A group of nanoengineers, biologists and physicists have used innovative approaches to deduce the internal structure of chromatin, a key player in DNA regulation, to reconcile a longstanding controversy in ...
Biochemistry
Jul 31, 2009
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0
DNA is the most important carrier of genetic information. Each cell contains approximately two meters of DNA. To ensure that all this genetic material fits into the small cell nucleus, it must be tightly packed. The DNA is, ...
Cell & Microbiology
Dec 4, 2023
0
1
Gene regulation relies on complex structural arrangements and processes at the molecular level. One of them, called 'chromatin loop extrusion', strikingly resembles the quick-lacing system of some trail running shoes: as ...
Cell & Microbiology
Dec 14, 2017
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7
Researchers from the Academy of Mathematics and Systems Science (AMSS) of the Chinese Academy of Sciences have teamed up with Stanford University and Tsinghua University scientists to successfully model data on gene regulation ...
Biotechnology
Jun 7, 2017
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2
Hybrid vigor refers to when a crossbreed plant or animal shows superior traits compared to its parents. A research group has discovered that a gene involved in maintaining DNA methylation is closely connected to hybrid vigor ...
Biotechnology
Oct 31, 2016
0
5
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, ...
Biotechnology
Apr 28, 2015
1
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