In nature, organic molecules are either left- or right-handed, but synthesizing molecules with a specific "handedness" in a lab is hard to do. Make a drug or enzyme with the wrong "handedness," and it just won't work. Now ...
Analytical Chemistry
Jan 10, 2024
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100
Chiral molecules exist in two forms, called enantiomers, which are mirror images of each other and non-superimposable—much like a pair of hands. While they share most chemical and physical properties, enantiomers can have ...
Biochemistry
May 26, 2022
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257
Atropisomers are a class of stereoisomers (chemical compounds that differ in spatial arrangement of atoms) arising from restricted rotation around a single bond and have various applications in chemistry. To date, most research ...
Materials Science
Feb 16, 2021
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7
Currently, various therapeutic compounds on the market, such as proteins, enzymes, and amino acids, are 'chiral compounds'—molecules with two structures that are mirror images of each other but cannot be superimposed. Although ...
Materials Science
Jun 29, 2020
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5
Chirality is a fundamental property of many organic molecules and means that chemical compounds can appear in not only one form, but in two mirror-image forms as well. Chemists at Martin Luther University Halle-Wittenberg ...
Materials Science
Jun 8, 2020
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19
Did you know that more than half of the drugs currently in use are chiral, potentially resulting in two different responses in the body? Chiral compounds are pairs of molecules that are mirror images of each other, just like ...
Materials Science
Feb 21, 2019
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6
Enantiomeric molecules resemble each other like right and left hands. Both variants normally arise in chemical reactions. But frequently, only one of the two forms is effective in biology and medicine. Completely converting ...
Materials Science
Dec 19, 2018
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12
Breaking carbon-hydrogen (C-H) bonds to alter existing molecules to create new ones is an increasingly important avenue for drug development. Of particular interest is mirror-image or "one-handed" compounds, but C-H breaking ...
Materials Science
Oct 23, 2014
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