How plants' threat-detection mechanisms raise the alarm

New work led by Carnegie's Zhiyong Wang untangles a complex cellular signaling process that underpins plants' ability to balance expending energy on growth and defending themselves from pathogens. These findings, published ...

Decoding the language of immune responses

Fever, cough, sore throat—symptoms in the spotlight in the era of COVID-19—are just some of the telltale signs of our body's immune system kicking into action against an unwanted intruder. Whether triggered by an infection, ...

Investigating a hospital superbug's resistance power

Treatment of severe infections caused by pathogenic bacteria relies on "last resort" antibiotics, but rising resistance by "superbugs" to most clinically approved drugs leaves patients exposed to possible fatalities.

A bacterial toxin that acts as a mediator rather than a killer

Traditionally, bacterial toxins have been seen as killers of target cells. But is there more than meets the eye? Umeå University Professor Teresa Frisan and her team have discovered that toxin-host interactions are more ...

Thinking afresh about how cells respond to stress

Just like people, cells get stressed too. A sudden drop in oxygen, overheating, or toxins can trigger a cascade of molecular changes that lead cells to stop growing, produce stress-protective factors, and form stress granules—proteins ...

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