Eukaryotes generate the energy for survival through cellular respiration in mitochondria by a process known as the oxidative phosphorylation. In this process, nutrients and oxygen are converted into a chemical form of energy: ...
Cell & Microbiology
Mar 27, 2023
0
109
By studying how enzymes move from one membrane compartment to another inside a cell, scientists at the University of Illinois Chicago have figured out a way to better target cellular proteins, which play a role in many diseases.
Biochemistry
Feb 15, 2023
0
90
Cholesterol is an essential component of the membrane surrounding every human cell, despite its poor reputation as a health concern when its blood levels are too high. The key to health is having the right amount of cholesterol ...
Biochemistry
Dec 12, 2022
0
24
Recent findings by UCSF and Arc Institute scientists open up new possibilities for overcoming a fundamental challenge in drug discovery. There can be a tradeoff between optimizing a drug's key-in-a-lock fit with its target ...
Cell & Microbiology
Dec 8, 2022
0
56
Nucleic acid therapies involving DNA or RNA have significant potential to treat genetic disorders, infectious diseases, and cancer; however, research suggests that less than 1% of injected nucleic acid doses reach target ...
Bio & Medicine
Nov 23, 2022
0
21
Inside cells, molecular droplets form defined compartments for chemical reactions. Not only sticky interactions between molecules, but also dynamic reactions can form such droplets, as was found by researchers from the Max ...
General Physics
Oct 27, 2022
0
48
Membrane proteins are key targets for many drugs. They are located between the outside and inside of our cells. Some of them, called transporters, move certain substances in and out of the cellular environment. Yet, extracting ...
Biochemistry
Oct 24, 2022
0
63
Understanding the family of cellular on/off switches known as G-proteins is important because these proteins control a lot of the communication between cells in the human body and beyond. A new study from the University of ...
Cell & Microbiology
Oct 21, 2022
0
2
"What our work shows is how a complex in the center of the cell, the ER-Golgi interaction region, controls plasma membrane cholesterol, which is essential for many cellular functions, if not essential for multicellular life," ...
Cell & Microbiology
Sep 28, 2022
0
37
Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids out of lysosomes, cellular organelles that are the breakdown factories of cells. The findings, ...
Cell & Microbiology
Sep 27, 2022
0
52
