Unexpected role of iASPP as a tumor suppressor
There is a tightly regulated balance between cell growth and death in healthy tissue. The loss of this balance is essentially what initiates cancer.
There is a tightly regulated balance between cell growth and death in healthy tissue. The loss of this balance is essentially what initiates cancer.
Cell & Microbiology
Oct 19, 2022
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Organisms grow to fit the space and resources available in their environments, leading to a vast diversity of body sizes and shapes within a population of the same species. What are the genetic and physiological mechanisms ...
Plants & Animals
Jun 8, 2022
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Quantitative Biosciences Institute (QBI) researchers at UC San Francisco have discovered a new paradigm for how fundamental biological switches, proteins that can be turned on and off to control processes like cell differentiation, ...
Molecular & Computational biology
Oct 14, 2021
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The capacity of a stem cell population to generate several distinct cell types in a temporally defined manner is fundamental to both organ development and homeostasis. To achieve this, stem cells must carefully balance self-renewal ...
Cell & Microbiology
Jun 5, 2020
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Even single cells are able to remember information if they receive the order from their proteins. Researchers at the University of Basel's Biozentrum have discovered that proteins form pairs to give the signal for storing ...
Cell & Microbiology
Jul 14, 2016
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Martin Evans received the Nobel Prize in Physiology or Medicine in 2007 for "for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells".
Cell & Microbiology
Jul 4, 2014
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In new research published online May 13, 2013 in Advanced Materials, researchers from Brigham and Women's Hospital (BWH) are the first to report that synthetic silicate nanoplatelets (also known as layered clay) can induce ...
Materials Science
May 14, 2013
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Researchers at the RIKEN Omics Science Center (OSC) have successfully developed and demonstrated a new experimental technique for producing cells with specific functions through the artificial reconstruction of transcriptional ...
Cell & Microbiology
Mar 14, 2012
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Scientists at the Genome Institute of Singapore (GIS) have recently generated significant single cell expression data crucial for a detailed molecular understanding of mammalian development from fertilization to embryo implantation, ...
Cell & Microbiology
Apr 21, 2010
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The regulation of important signal molecules that are critical for the formation of various cell types can be influenced by a chemically produced variant of indirubin, a natural material used in traditional Chinese medicine. ...
Cell & Microbiology
Nov 30, 2012
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