Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer—lysosomal membrane permeabilization, or LMP for short—can ...
Cell & Microbiology
Apr 8, 2024
0
17
Chromosomal instability is a phenomenon characterized by rapid changes in the number and structure of chromosomes during cell division. It is very common in solid tumors and it is linked to the aggressive spread of cancer, ...
Cell & Microbiology
Sep 26, 2023
0
12
Naked mole-rats have the longest life span among all rodents and can resist aging and the age-related diseases. However, the precise mechanisms underlying this ability are largely unclear.
Cell & Microbiology
Aug 18, 2023
0
36
A study by Loughborough University and the University of Oxford has led to the development of a small molecule probe that could deepen our understanding of a crucial cellular messenger and lead to the development of new therapeutic ...
Biochemistry
May 30, 2023
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53
Particles known as extracellular vesicles play a vital role in communication between cells and in many cell functions. Released by cells into their environment, these "membrane particles" consist of a cellular membrane carrying ...
Bio & Medicine
May 24, 2023
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97
Collaborative research at the University of Cincinnati has developed a new probe to better study cells that has already led to new knowledge about certain cellular processes.
Molecular & Computational biology
May 8, 2023
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8
Researchers at the Universitat Pompeu Fabra (UPF), ICREA, CIBERNED, CNIC and Altos Labs, among other national and international collaborators, have characterized how damaged cells (senescent cells) that inevitably arise after ...
Cell & Microbiology
Dec 21, 2022
0
20
Metal-containing complexes have taken up center stage in the search for new cancer drugs that are as free of side effects as possible. In the journal Angewandte Chemie, a research team has now described how a very low dose ...
Biochemistry
Oct 12, 2022
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44
A set of genes that promote sweet taste sensation is also crucial for protein management during fly development, according to a new study by Eugenia Piddini of the University of Bristol, United Kingdom, and colleagues, publishing ...
Cell & Microbiology
Jul 21, 2022
0
40
Aging and age-related disorders pose a complex challenge to the biomedical research community. To better understand how senescence is regulated is of high significance to promote healthy aging and treat age-associated disorders. ...
Cell & Microbiology
Jul 18, 2022
0
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